Month: May 2026

Independent Study by UNLV

What Genetic Sequencing Revealed About FritzZyme TurboStart 700

FritzZyme TurboStart 700 lists Nitrosomonas and Nitrobacter, nitrifying bacteria, on the label. In 2011, a microbiology lab at the University of Nevada, Las Vegas confirmed those genera are actually in the bottle — not because they set out to validate the product, but because their own research required them to know exactly what they were working with.

Chosen for a reason

The UNLV team, led by Professor Penny Amy, needed a reliable source of live nitrifying bacteria to seed a soil-free plant growth system. They chose FritzZyme TurboStart 700 because earlier work had already shown it establishing real nitrification in zeoponics, a demanding semi-hydroponic system.

What they confirmed

Working with the UNLV Genomics Center, the team used 16S rDNA gene sequencing — a method that identifies bacteria by their genetic signature. The results came back with exactly two nitrifying genera: Nitrosomonas (ammonia-oxidizing) and Nitrobacter (nitrite-oxidizing). The same two Fritz lists on the label.

They also confirmed the bacteria were alive and active. Tracking cultures over several days, they measured real ammonia and nitrite oxidation — which is the process of nitrification in the nitrogen cycle.

Why it matters

True nitrifying bacteria are autotrophs: they get their energy from ammonia and nitrite, grow slowly, and are difficult to keep alive in a bottle. From our own experience, many commercial products instead use only shelf-stable spore-forming heterotrophic bacteria — which, although beneficial, do not perform the nitrogen cycle. The UNLV results confirm FritzZyme contains the real thing.

Reference: Harrington A., Perry J., Amy P.S. “Identification of nitrifying bacteria contained in a commercial inoculant using molecular biology techniques.” UNLV School of Life Sciences, Undergraduate Research Opportunities Program, 2011.

Related Articles

The Complete Nitrogen Cycle

Every healthy aquarium or aquatic system depends on a functioning nitrogen cycle. Understanding how the cycle works is the first step toward a stable, healthy aquarium.

The nitrogen cycle can be broken down into two parts: mineralization and oxidation. Through these processes, organic material is converted into ammonia, then to nitrite, and finally to nitrate.

Mineralization: breaking down waste

Through mineralization, heterotrophic bacteria (not nitrifiers) break down complex proteins and organics into ammonia. These “sludge eating” Bacillus bacteria break down solid waste, excess food and sludge. Each Bacillus species has a unique, preferred food source. Some species break down carbohydrates; others feed on proteins. FritzZyme® TurboClean contains billions of these necessary, tank-cleaning bacteria. By incorporating high concentrations of these bacteria, TurboClean significantly reduces messy maintenance and odor. Unlike their nitrifying cousins, the Bacillus in TurboClean multiply very rapidly and can live in a broad range of water conditions. Select species thrive in both fresh and saltwater. They multiply so rapidly that the population consumes all its food and dies. They cannot be sustained long-term in large numbers in a tank. Nitrifiers need only be added when the system is first set up, but Bacillus bacteria should be added two times per month to sustain a stable, abundant population. Without a large quantity of Bacillus bacteria, solid waste would pile up in the tank and within the filter. Nitrification would not take place.

Oxidation: the role of nitrifying bacteria

Through oxidation, nitrifiers break down ammonia. The oxidation of ammonia (NH₃) to nitrite (NO₂) is performed in freshwater by Nitrosomonas bacteria. Nitrite (NO₂) is then converted to nitrate (NO₃) by bacteria of the genus Nitrobacter. It is well-known that taking the filter media out of a freshwater tank and adding it to a saltwater tank won’t instantly cycle the marine system; this is because different bacteria (Nitrosococcus and Nitrococcus) perform oxidation in saltwater. Due to their unique ability to oxidize ammonia and nitrite, these four genera of bacteria have been identified by microbiologists throughout the world as the true nitrifying bacteria (Dr. James E. Alleman, Ph.D. and Kurt Preston, Purdue University, “Behavior and Physiology of Nitrifying Bacteria”).

The bio-filter: building a home for bacteria

A bio-filter is a “hotel.” Bio-media within the filter acts like “hotel rooms” for the bacteria to grow on. With more media, you can house more bacteria. The more bacteria you have, the faster deadly levels of ammonia and nitrite can be eliminated. For best results, use 1-2 cubic feet of bio-media initially per 100 gallons for an average-load system. Ideally, the bio-media should yield the highest surface area possible (to which the bacteria attach) without trapping sludge. When media traps sludge, areas of low flow, oxygen and pH are created, in which the nitrifying bacteria will not grow, causing ammonia and nitrite imbalances. For a stable, healthy tank, you need an established population of these bacteria in the filter.

Putting nitrifying bacteria to work

FritzZyme® 7 and 9 and TurboStart® 700 and 900 contain high concentrations of naturally occurring nitrifying bacteria and significantly reduce cycling time — typically a few days instead of several weeks or longer — because introducing a large, established population of nitrifying bacteria is the natural way to start a healthy aquarium. These products are also ideal for use after the initial cycle to fortify a biofilter that has become diminished due to medication, water quality, or equipment failure. TurboStart is used by many public aquariums, aquaculture facilities, zoos, research facilities, and retail stores and hobbyists worldwide.

Did you know?

  • The nitrogen cycle exists in every healthy body of water on earth, from the ocean to a backyard pond

  • Nitrifying bacteria establish themselves on almost every surface in a healthy aquarium — filter media, substrate, decorations, and even the glass

  • A well-established biofilter can process ammonia continuously, 24 hours a day

  • Fritz Industries was the first company to cultivate nitrifying bacteria commercially — over 40 years ago

Related Articles

Preferences of Nitrifying Bacteria

Nitrifying bacteria are beneficial microorganisms that drive the nitrogen cycle in natural aquatic ecosystems and the small self-contained ecosystem of an aquarium. They establish themselves on various surfaces in the aquarium to function as a biological filter, converting toxic ammonia to nitrite, then nitrite to less toxic nitrate. Like any living organism, they have specific environmental preferences that affect how well they grow and perform. In this article we cover those preferences — including temperature, pH, dissolved oxygen, salinity, and the effects of common chemicals — so you can create the best possible conditions for your biofilter.

Products like FritzZyme® 7 and TurboStart® 700 for freshwater, FritzZyme® 9 and TurboStart® 900 for saltwater, introduce concentrated cultures of live nitrifying bacteria to establish or restore that biological filter quickly.

Medication & nitrifying bacteria

Nitrifying bacteria are gram-negative rods up to 2 microns long. Unlike pathogens, nitrifiers are non-pathogenic and beneficial — but because most antibiotics target gram-negative bacteria broadly, they affect nitrifiers and pathogens equally. Other inhibitory chemicals include formalin, formaldehyde, chlorine, chloramine, malachite green, methylene blue, acriflavine, household disinfectants, copper (at 0.20 mg/L or higher), potassium permanganate, and chloroquine. Always perform a 30% water change and add fresh activated carbon after using any of these chemicals to remove residual byproducts. Then reintroduce nitrifying bacteria to restore the biofilter.

Chemical ammonia removers & nitrifiers

Ammonia removers must be evaluated carefully since different formulations pose different risks. Avoid any containing formalin — whether cycling or not. Formalin (a form of formaldehyde) inhibits nitrifiers already established in the filter, as well as those in bottled bacterial products. Many ammonia removers also drop pH; others introduce phosphates. If your tap water contains chloramine, use FritzGuard® followed immediately by Fritz A.C.C.R. to address the ammonia left behind.

UV sterilizers, protein skimmers & ozone generators

Nitrifiers prefer to attach to filter surfaces after the initial inoculation period, which takes approximately five days under optimal conditions. Until attached, the bacteria are vulnerable to removal by mechanical and chemical filtration equipment. Turn off UV sterilizers, ozone generators, and protein skimmers, and remove sub-micron mechanical filter media (5 microns or less) before adding bacteria. Wait five days before turning them back on.

Temperature & salinity

Cycling within the optimal temperature range of 77–86°F produces the best results. Cold water tanks should be lowered slowly over several days after cycling is complete. If a system cannot be cycled within this range, use double the standard dosage and expect the process to take longer. Nitrobacter/Nitrococcus are more sensitive to low temperatures, making nitrite problems more likely in cold water tanks. Freshwater nitrifiers tolerate salinities of 0–20 ppt, while saltwater nitrifiers prefer 20–44 ppt.

pH and alkalinity

Due to differences in pH preferences, fresh and saltwater systems tend to accumulate different compounds during cycling — marine hobbyists should watch nitrite levels closely, while freshwater hobbyists should monitor ammonia. pH stability is critical for nitrifying bacteria. The nitrification process consumes bicarbonates and produces carbon dioxide, which lowers pH over time. If alkalinity is initially low, pH swings can be significant. Starting bicarbonate levels of 100–200 mg/L are recommended.

Dissolved oxygen

Nitrification stops below 2–3 mg/L of dissolved oxygen (DO). Complete oxidation of ammonia requires 4.57 mg of oxygen per 1 mg of ammonia. For best results, DO levels should be above 80% saturation — at least 6 mg/L. Nitrobacter/Nitrococcus are particularly sensitive to low DO; nitrite problems typically follow when levels drop. Biofilters can accumulate sludge over time, restricting flow through parts of the filter — a condition called channeling. Channeling promotes anaerobic bacteria, produces toxic compounds, and inhibits nitrifiers. Regular addition of heterotrophic bacteria, such as those found in FritzZyme® TurboClean, helps eliminate sludge and prevent anaerobic pockets in both the filter and substrate.

Odor and appearance

Nitrifying bacteria cultures have a slightly earthy smell and range from rosy to dark brown in color. Color and odor vary slightly between batches and are not indicators of viability. Each batch is individually tested and must pass quality control before shipping. Always use before the expiration date printed on the bottle.

Maintenance at a glance

Daily

  • Observe fish behavior
  • Check temperature
  • Remove uneaten food
  • Check equipment

Weekly

  • Headcount livestock
  • Check for algae
  • Top off evaporation

Biweekly

  • Test water parameters
  • 10–20% water change
  • Vacuum substrate
  • Clean glass
  • Rinse filter media in tank water
  • Replace carbon and filter floss
  • Inspect equipment

Monthly

  • Inspect filter internals
  • Clean pump impellers and intakes
  • Review stocking levels
  • Compare test results to previous months

Aquarium Maintenance Tips

Consistent maintenance is how fishkeepers suceeed. A regular schedule keeps water parameters stable, catches problems early, and keeps fish healthy long term.

Water changes

A partial water change of 10–20% every two weeks is a good baseline for most tanks — more frequently if the tank is heavily stocked or if parameters are off.

Always treat new water before adding it to the tank. Tap water can contain chlorine, chloramine, and heavy metals that are harmful to fish and beneficial bacteria. Local tap water may also contain phosphates, iron, and other compounds that can affect water chemistry — contact your local water utility if you’re unsure what’s in your supply.

Testing

Test regularly to stay on top of what’s happening in your tank. The key parameters to monitor are:

  • Ammonia — should always be 0 ppm
  • Nitrite — should always be 0 ppm (except during the initial cycling period)
  • Nitrate — keep below 20 ppm for most freshwater fish, below 10 ppm for saltwater, reef, and sensitive species
  • pH — 6.8–7.4 for most freshwater fish, 8.1–8.3 for marine aquariums
  • Carbonate hardness (KH) — a measure of your water’s buffering capacity, or its ability to resist pH swings. Low KH makes pH unstable and harder to manage
  • Salinity — essential for saltwater and brackish tanks; see our Salinity article for target ranges
Recommended maintenance routine

Daily

  • Observe fish behavior — changes in activity, appetite, or appearance can be the first sign of a water quality issue
  • Check water temperature — sudden swings in either direction can stress or kill fish
  • Remove any uneaten food — excess food breaks down quickly and can trigger ammonia spikes
  • Check equipment to confirm everything is running properly
  •  

Weekly

  • Do a quick headcount of livestock. A dead fish can decompose rapidly and trigger a significant ammonia spike before you notice it
  • Check for algae buildup on glass and surfaces
  • Top off evaporation with treated fresh water (saltwater tanks only)

Biweekly

  • Test ammonia, nitrite, nitrate, pH, carbonate hardness, and salinity (saltwater and brackish tanks)
  • Perform a 10–20% water change
  • Vacuum the substrate to remove accumulated waste
  • Clean aquarium glass
  • Rinse filter media in tank water — never tap water, which can kill beneficial bacteria
  • Replace carbon and filter floss if present
  • Inspect all equipment for proper operation

Monthly

  • Do a deeper inspection of filter internals and replace any worn components
  • Check and clean pump impellers and intakes
  • Review livestock health and stocking levels — overcrowding is one of the most common causes of persistent water quality problems
  • Compare current test results to previous months to catch slow shifts before they become problems
Conclusion 

Good maintenance isn’t about perfection, it’s about consistency. Stay on schedule, keep testing, and address small problems before they grow — and you’ll enjoy a healthy, thriving aquarium for years to come.

Maintenance at a glance

Daily

  • Observe fish behavior
  • Check temperature
  • Remove uneaten food
  • Check equipment

Weekly

  • Headcount livestock
  • Check for algae
  • Top off evaporation

Biweekly

  • Test water parameters
  • 10–20% water change
  • Vacuum substrate
  • Clean glass
  • Rinse filter media in tank water
  • Replace carbon and filter floss
  • Inspect equipment

Monthly

  • Inspect filter internals
  • Clean pump impellers and intakes
  • Review stocking levels
  • Compare test results to previous months

The ABCs of Water Quality

Water chemistry is the balance of dissolved minerals, salts, and organic compounds in your tank water — and it directly affects the health of everything living in it. The key areas to understand are the nitrogen cycle (how beneficial bacteria convert ammonia to nitrite, then nitrate), pH, water hardness, and salinity. Getting these parameters right and keeping them stable is what separates a healthy, low-maintenance tank from one that’s constantly fighting problems.

Start with properly conditioned water

Tap water, well water, RO, and DI water all need to be treated before being added to a fresh or saltwater aquarium. Municipal water contains chlorine, chloramine, and heavy metals that are toxic to fish, invertebrates, and the beneficial bacteria that keep your tank stable.

FritzGuard® neutralizes chlorine, chloramine, and heavy metals instantly, and helps speed up the tank cycle by helping beneficial bacteria establish in the filter.

Manage ammonia and nitrite

Once fish are added, ammonia and nitrite levels can climb to toxic levels within days. Overfeeding, water changes, new fish additions, and medications can all trigger imbalances — even in established tanks. These are the most common causes of fish loss and are largely preventable with regular testing.

Nitrifying bacteria are the most effective tool for keeping ammonia and nitrite in check. FritzZyme® 7 for freshwater and FritzZyme® 9 for saltwater contain live, concentrated cultures that rapidly convert ammonia and nitrite into less toxic nitrate. Test regularly and add FritzZyme® whenever any ammonia or nitrite is measured.

Test regularly

Regular testing of important water parameters is a good habit for keeping a healthy ecosystem for your fish. Most water quality problems develop gradually and show no visible signs until they reach a critical level — by the time fish are visibly stressed, the issue has often been building for days. Testing ammonia, nitrite, nitrate, and pH on a consistent schedule gives you the information needed to catch problems early and correct them before fish are at risk. A good test kit is one of the most valuable tools in the hobby.

Water changes

Regular water changes are essential for long-term tank health. Even a well-maintained tank accumulates nitrates, organic waste, and other compounds over time that filtration alone can’t fully address. A routine of small, frequent water changes keeps parameters stable and reduces stress on fish. Always treat replacement water with a water conditioner before adding it to the tank.

Keep up with maintenance

Even a well-running tank accumulates waste over time. Organic debris settles into the substrate, collects in filter media, and breaks down into compounds that fuel ammonia spikes and inhibit beneficial bacteria. Watch your fish for early signs of trouble — lethargy, discoloration, or loss of appetite often signal a water quality issue before your test kit does.

FritzZyme® TurboClean uses naturally occurring bacteria to break down organic waste in the substrate and filter media without affecting water chemistry.

Dealing with cloudy water

Cloudy water is one of the most common aquarium frustrations. It can appear as a white haze or general discoloration, and it often gets worse — not better — with water changes and filter cleaning. Fritz Crystal Clear is a clarifying agent safe for use in fresh and saltwater tanks with fish, plants, and corals.

Learn more

For deeper dives into specific parameters, see our articles on Ammonia, Nitrite, Nitrate, pH, Salinity, and Chloramine.

Water Quality Checklist

  • Treat all water with a dechlorinator before adding it to the tank

  • Establish and maintain a healthy biological filter with nitrifying bacteria

  • Test ammonia and nitrite daily during the cycling period — target is always 0 ppm

  • Once cycled, test ammonia, nitrite, nitrate, and pH at least monthly

  • Perform regular small water changes to keep nitrates and organic waste in check

  • Watch fish daily for signs of stress — lethargy, clamped fins, loss of appetite, or discoloration

  • Keep up with filter and substrate maintenance to prevent waste buildup

  • Address any parameter outside the normal range before it becomes a bigger problem

About Salinity

Salinity is a measure of the total amount of dissolved salts in water. Seawater is not simply salt dissolved in water — it is a complex solution containing calcium, magnesium, potassium, and dozens of other trace elements that marine life depends on. In marine and brackish aquariums, salinity is one of the most critical parameters to monitor and maintain. The ocean averages between 34 and 37 ppt of dissolved salts.

How salinity is measured

Salinity can be measured two ways: directly in parts per thousand (ppt), or indirectly through specific gravity. Most hobbyists use specific gravity because it is easy to measure with a hydrometer or refractometer.

Specific gravity is the ratio of the density of your aquarium water to the density of pure water. Pure water has a specific gravity of exactly 1.000. Saltwater is denser than pure water, so its specific gravity is higher — the more dissolved salt, the higher the reading. The specific gravity of natural seawater at 35 ppt is 1.026.

Tools for measuring salinity

Three tools are commonly used: a swing-arm hydrometer, a refractometer, and a digital refractometer. Swing-arm hydrometers are the most affordable but least precise, refractometers are more accurate and better suited for reef tanks, and digital refractometers are the most precise and easiest to read. Whichever you use, rinse and calibrate regularly.

Target ranges
  • Reef aquariums — 1.024 to 1.026 specific gravity (34–36 ppt). Coral and invertebrates are sensitive to salinity variation, so consistency within this range is important

  • Fish-only marine aquariums — 1.020 to 1.024 specific gravity. Fish generally tolerate this lower range well, and the reduced salinity makes conditions harder for parasites like ich

  • Brackish aquariums — 1.002 to 1.022 specific gravity. The right level within this wide range depends on the species — research the natural habitat of your fish, as some prefer conditions closer to freshwater while others do best closer to full marine salinity
Why salinity changes over time

Because of evaporation, salinity in your tank will rise gradually over time. Salt does not evaporate — only water does. As water evaporates, the same amount of dissolved salt remains in a smaller volume of water, increasing concentration. This is why topping off your tank with fresh water — not saltwater — is the correct way to compensate for evaporation. Only add new saltwater when doing a water change.

Salinity fluctuations stress fish and invertebrates. Top off with fresh water as often as needed to keep levels stable. For tanks with high evaporation rates, an automated top-off system can keep salinity stable without the daily monitoring.

Salt in freshwater aquariums

Most typical freshwater aquariums do not require salt. However, aquarium salt dissolves into electrolytes — the ions fish need for oxygen uptake and the release of carbon dioxide and ammonia through the gills. When needed, adding a small amount can reduce stress, support disease recovery, and help treat certain internal issues like constipation and mild swim bladder disorders.

Always use salt specifically formulated for aquariums, like Fritz A+ Aquarium Salt, never use regular table salt. Food-grade salt typically contains iodine and anti-caking agents that are harmful to fish and beneficial bacteria.

Aquarium salt does not evaporate and is not filtered out, so it should only be added with each water change. Some aquatic plants are sensitive to salt — use with caution in planted tanks.

Why salt quality matters

Not all aquarium salts are created equal. Raw material quality, elemental ratios, and batch consistency all affect your tank’s health more than most hobbyists realize. A well-formulated salt dissolves clearly, hits stable chemistry quickly, and covers the full range of elements your tank needs. Poor quality salt is a common source of problems that are hard to diagnose.

Fritz salt products
  • RPM Complete Marine Salt
  • A+ Aquarium Salt
  • African Rift Lake Cichlid Salt

Salinity Quick Facts

  • Seawater is not just salt — it contains calcium, magnesium, potassium, and other of trace elements

  • Salinity is measured in parts per thousand (ppt) or specific gravity (SG)

  • Salt does not evaporate — always top off with fresh water, not saltwater

  • Never use table salt in an aquarium, it contains iodine and anti-caking agents harmful to fish

About pH

The pH scale measures how acidic or alkaline your aquarium water is. The term stands for “Power of Hydrogen” — a reference to the concentration of hydrogen ions in the water, which determines where it falls on the scale. The scale runs from 0 to 14. A pH of 7.0 is neutral. Below 7.0 is acidic, above 7.0 is alkaline (also called basic). The further from 7.0 in either direction, the more extreme the condition.

One important thing to understand: the pH scale is logarithmic, not linear. Each whole number step represents a tenfold change in acidity or alkalinity. Water with a pH of 6.0 is ten times more acidic than water with a pH of 7.0, and one hundred times more acidic than water with a pH of 8.0. Small shifts that look minor by number can represent significant changes in water chemistry.

Why pH matters in an aquarium

More than any other parameter, pH has a broad influence on fish health and water chemistry. It affects the toxicity of ammonia — the more toxic NH₃ form increases as pH rises. It influences how efficiently your biological filter functions, how well fish regulate their internal chemistry, and how easily disease sets in. Stable pH, in the right range for your fish, is one of the most important factors in a healthy tank.

Sudden swings are often more dangerous than a pH that is slightly outside the ideal range. Fish can acclimate gradually to an imperfect pH, but a rapid shift — even toward a more favorable value — can cause osmotic shock and death.

pH ranges for common aquarium fish

Most community freshwater fish and plants do best between 6.8 and 7.4, though fish can survive across a fairly wide range. Different species have different preferences:

  • Acidic water (below 7.0) — tetras, discus, angelfish, and many South American species prefer softer, more acidic conditions
  • Neutral to slightly alkaline (7.0–7.6) — most community fish, goldfish, and the majority of aquarium plants thrive here
  • Alkaline water (above 7.6) — livebearers such as mollies and guppies, and African cichlids, prefer harder, more alkaline conditions
  • Saltwater tanks — marine aquariums typically require a stable pH between 8.1 and 8.3
What causes pH to change

In an aquarium, pH is not static — it shifts over time in response to several factors:

  • CO₂ levels — carbon dioxide dissolves in water to form carbonic acid, which lowers pH. In a heavily planted tank or one with a high fish load, CO₂ buildup can cause pH to drop, especially overnight when plants consume oxygen rather than produce it
  • Biological activity — the nitrogen cycle produces acids as a byproduct, gradually lowering pH over time in an established tank
  • Tap water variability — municipal water pH can vary seasonally, introducing unexpected shifts during water changes
  • Substrate and decor — limestone, coral, and crushed coral raise pH; driftwood and peat lower it
  • Evaporation — as water evaporates, dissolved minerals concentrate, pushing pH upward
Testing and target levels

Test pH weekly — more frequently than some other parameters, but worth it given how much pH influences the toxicity of other compounds in your water. Use a reliable test kit at the same time of day each time, since pH can fluctuate naturally throughout the day, particularly in planted tanks. Logging your readings over time helps catch slow shifts before they become a problem.

Adjusting pH

Make changes gradually. A shift of more than 0.2 per day is generally considered stressful for fish. Avoid chasing a perfect number — consistency matters more than hitting an exact target.


Fritz pH control products

pH Quick Facts

  • Most freshwater community fish do best between 6.8 and 7.4

  • Marine aquarium pH typically fall between 8.1 and 8.3

  • Stability is more critical than hitting an exact number, sudden pH swings are often more dangerous than a pH that is slightly but consistently out of range

  • Test pH weekly — it directly influences the toxicity of ammonia and other compounds in your water

About Nitrites

Nitrites are one of the most harmful compounds found in aquarium water, yet they are a natural part of the nitrogen cycle that keeps your aquarium healthy. Nitrite is produced when beneficial nitrifying bacteria in the biological filter convert ammonia as part of the nitrogen cycle. As the biological filter matures, bacteria consume nitrite and convert it into nitrate, slowly lowering nitrite levels in the aquarium.

Why nitrites are dangerous

Even low levels of nitrite are harmful. Nitrite directly affects the red blood cells of fish, reducing their ability to carry oxygen — which can lead to suffocation and death if ignored. This makes nitrite one of the few water quality issues where there is no safe “low level.” The target is always zero.

When to watch for nitrite spikes

Nitrite levels are most likely to spike during the startup of a new tank, when the biological filter hasn’t fully established yet. This is a critical period that can stress or kill fish if not managed carefully. Even in a mature, cycled tank, nitrite spikes can occur — triggered by overfeeding, a sudden increase in livestock, a water quality disruption, or the death of a fish. Any elevation above 0 ppm is a sign that something in the tank is off.

Testing and target levels

Include nitrite testing as part of your monthly routine. If a fish appears ill or dies unexpectedly, test for nitrite right away to make sure it isn’t part of the problem. Use a Fritz Nitrite Test Kit to check your levels. Nitrite should always read 0 ppm — any detectable amount is a problem worth addressing right away.


Corrective actions
  • If nitrite is present, act quickly
  • Temporarily reduce feeding if any nitrite or ammonia is detected
  • Perform a partial water change if nitrite levels exceed 0.5 ppm
  • Remove as much waste from the bottom of the aquarium as possible
  • Treat replacement water with FritzGuard® Water Conditioner to reduce fish stress and the chance of infection
  • Add FritzZyme® 7 Freshwater or FritzZyme® 9 Saltwater Nitrifying Bacteria to fortify your bio filter and reduce ammonia and nitrite naturally
  • For fastest-possible results or heavily stocked systems, use TurboStart® 700 or TurboStart® 900 — a super-concentrated nitrifying bacteria formula for rapid ammonia and nitrite elimination

Nitrite Quick Facts

  • There is no safe “low level” — nitrite should always read 0 ppm

  • Nitrite reduces the ability of fish to carry oxygen, which can lead to suffocation and death

  • Spikes can happen in new or established tanks — monthly testing is recommended

  • If nitrite is detected, act quickly: reduce feeding, do a partial water change, and remove waste

About Nitrates

Nirate Quick Facts

  • Nitrates are less toxic than ammonia or nitrite, but harmful at elevated levels
  • High nitrates cause chronic stress, increase chance of disease and feed nuisance algae growth
  • Regular water changes are the best way to keep nitrate levels low
  • Keep levels below 20 ppm for most freshwater fish, below 10 ppm for saltwater tanks and more sensitive species

Nitrates (NO₃⁻) are the final byproduct of the nitrogen cycle. They are produced by beneficial nitrifying bacteria (such as Nitrospira and Nitrobacter) that convert nitrites into this less immediately toxic compound — this process is where the term “nitrification” comes from. They also accumulate from the ongoing breakdown of organic matter: uneaten food, fish waste, and decaying plant material.

Why nitrates are a problem

While nitrates are far less immediately toxic than ammonia or nitrite, elevated levels create chronic stress that weakens immune function and leaves fish vulnerable to disease outbreaks, bacterial infections, and parasites. High nitrates are also a primary driver of nuisance algae growth, since algae readily consume nitrates as a nutrient source.

Keeping nitrates under control

Because nitrates build up continuously, unlike ammonia and nitrite which a healthy biofilter processes and removes, staying on top of nitrate levels is important. Regular water changes are the most reliable method for keeping levels in check. Live plants can help by consuming nitrates as nutrients, and certain specialized filter media can reduce them by supporting bacteria that break nitrates down further. That said, water changes remain the most effective tool for managing nitrates in most aquariums.

Testing and target levels

Testing nitrate levels monthly is a good starting point for established tanks, but more frequent monitoring is recommended when breeding fish or raising fry (juvenile fish). Juvenile fish are significantly more sensitive to nitrate toxicity than adults, making low, stable levels especially important during early life stages. As a general target, keep nitrates below 20 ppm for most freshwater fish and below 10 ppm for sensitive species, saltwater tanks, and breeding setups.

About Chloramine

Quick Chloramine Facts

  • Chloramine is added tap water in municipal water treatment plants

  • Chloramine is chlorine bonded to ammonia — standard dechlorinators remove the chlorine but leave the ammonia behind

  • The ammonia left behind is toxic to fish, even at low levels

  • The easiest solution is a water conditioner that handles both chlorine and ammonia in one step

If your water comes from a municipal supply, there’s a good chance it contains chloramine — and standard dechlorinators won’t fully handle it. Chloramine is a compound used to disinfect drinking water. Unlike chlorine, which dissipates quickly, chloramine is stable and persistent, which is why water treatment plants have increasingly adopted it. If you’re not sure whether your local water supply uses chlorine or chloramine, contact your water utility and ask.

Why chloramine is a problem for aquariums

The same chemicals that make tap water safe to drink can be highly toxic to fish and the beneficial bacteria that keep your tank stable. Chlorine is relatively simple to remove — it reacts quickly with sodium thiosulfate-based dechlorinators and is neutralized instantly. Chloramine is more complicated.

Chloramine is chlorine bonded to ammonia (NH₃). Standard dechlorinators will break that bond and neutralize the chlorine — but the ammonia is left behind, free in the water. Using a basic dechlorinator on chloramine-treated water solves one problem while creating another.

Understanding the ammonia left behind

The toxicity of the remaining ammonia depends largely on the pH of your water. Ammonia exists in two forms: the more toxic unionized form (NH₃) and the less toxic ionized form (NH₄⁺, also called ammonium). At lower pH levels, ammonia is more likely to exist as NH₄⁺. As pH rises above 7.0, the balance shifts toward the more toxic NH₃ form. The same ammonia reading can represent a very different level of risk depending on your water’s pH — saltwater tanks, which run at a higher pH, are particularly vulnerable.

How to remove chloramine

There are a few approaches, and the best one depends on your setup.

The easiest option is to use a water conditioner specifically formulated to handle chloramine — one that neutralizes both the chlorine and the ammonia together. Fritz A.C.C.R. and Fritz Complete Water Conditioner both detoxify ammonia in addition to removing chlorine, making them a good fit for chloramine-treated tap water.

If you prefer to remove the chlorine and address the ammonia separately, sodium thiosulfate handles the chlorine portion quickly and inexpensively. From there, you have a few options for the ammonia:

  • A healthy, well-established biological filter may be sufficient to handle the ammonia load on its own, particularly at lower pH levels and with a moderate fish load. To test whether your filter can keep up, start with small water changes — around 5% — and increase gradually while monitoring ammonia levels closely. If you see signs of stress at any level, your filter may not be keeping up.
  • If your filter can’t keep up, increasing aeration and biological filtration capacity will help. In some cases, aquarists manage ammonia by reducing fish load, upgrading to a higher flow rate filter, or adding reverse osmosis water to lower pH and reduce NH₃ toxicity.
The simplest approach for most hobbyists

For most home aquariums, the easiest and most effective option is a water conditioner that handles both chlorine and ammonia in a single step. Treat your replacement water before or as you add it to the tank — the reaction is instant, no need to mix and wait. Follow the product dosage instructions based on your tank volume.