FritzZyme® 460 Saltwater Aquarium Cleaner

  • Biological aquarium cleaner for saltwater
  • Promotes a clean, clear and healthy aquarium
  • Reduces and simplifies maintenance
  • Bacteria rapidly digest waste
  • Eliminates foul odors
  • Biologically assists nitrification
  • Improves water clarity
  • Improves flow through filters

About FritzZyme® 460 Saltwater Aquarium Cleaner

FritzZyme® 460 is a powerful probiotic blend of naturally occurring, environmentally friendly, live heterotrophic bacteria capable of digesting organic sludge common in aquariums. Sludge includes fish waste, leftover food and other decaying organic matter. Using FritzZyme® 460 as part of a regular maintenance program will greatly reduce aquarium care including gravel vacuuming, water changes as well as prolonging filter media life.

Rather than relying on freshwater bacteria to treat both fresh and saltwater, Fritz Industries has identified the species that naturally occur and perform best for each environment. FritzZyme® 460 contains only species of bacteria native to saltwater. The bacteria in FritzZyme® 460 is safe, non-toxic and non-pathogenic.

Directions & Dosage

Initial dose: Use 1 tsp (5 ml) per 5 US gallons (19 L).
Maintenance dosing: Use 1 tsp (5 ml) per 10 gallons (38 L).
Shake well, add directly to aquarium in an area of high flow to allow product to circulate. Turn off UV sterilizers for 48 hours after application.

NOTE: An earthy odor is normal, a natural result of biological activity. Odor will quickly dissipate when adding product to aquarium. Color variation is normal.


Size Treats Item Number
8 oz. 473 gal. 83369
16 oz. 946 gal. 83370
32 oz. 1,892 gal. 83372
1 gal. 7,570 gal. 83373



See below for frequently asked questions regarding FritzZyme® 460 Saltwater Aquarium Cleaner.

  • Does FritzZyme® 460 get rid of cyanobacteria/red slime algae?

    Yes, Fritz has not conducted formal, rigorous studies of this. Over time, the bacteria in FritzZyme® 460 outcompete cyanobacteria for nutrients causing the cyanobacteria to recede. But with that said, this does not happen overnight.

  • How long has Fritz Industries, Inc. been working with nitrifying bacteria?

    Fritz Industries, Inc. has been working with nitrifying bacteria for over 26 years and has constantly worked to perfect culturing techniques while obtaining maximum production with superior packaging of a stabilized product.

  • What products should not be used with FritzZyme®?

    U.V. sterilizers, foam fractionators (protein skimmers) and ozone generators should not be used for at least 7-10 days after FritzZyme® additions. This allows the bacteria time to become attached so that they will not be killed or removed by these types of equipment. Many medications will also reduce the efficiency of the biofilter.

  • What sets Fritz Industries’ nitrifying bacteria products apart from other competitors?

    Fritz Industries is the only known company growing viable nitrifying bacteria with a shelf life of over 30 days, and no other company can compare to the concentration levels of viable bacteria.

  • Will Maracyn or another Fritz product work on cyanobacteria?

    Health Canada has taken Erythromycin of the pet store shelves. I have used it to treat cyanobacteria (“blue-green algae”) in the past with unfailing success. Can you please advise if Maracyn or another Fritz product will work on cyanobacteria.

    The only product we have that can be sold in Canada is our FritzZyme 360 & 460. These are biological products that will compete with cyano.  Although not a quick fix like Erythromycin, using as a regular part of maintenance will help prevent cyano breakouts.

  • How does FritzZyme® compare to other products?

    FritzZyme® was the first product on the market to rapidly establish biological filters in aquatic systems. Having been on the market for over 15 years, it is the only time-proven product of its kind, becoming known as “the bacteria that works.” Since over 75% of the ammonia generated within the aquarium comes from direct excretion from the fish, it only makes sense to use bacterial products which provide the nitrifying bacteria to utilize this ammonia. If the product will not utilize ammonium chloride, it will not utilize the excreted ammonia. Therefore, although other products have been introduced on the market with many claims, be assured there is only one tested, proven FritzZyme®.

    In addition to FritzZyme® being sold throughout the pet industry, the Fritz Pet division supplies FritzZyme® to professional fish, shrimp and lobster farms, city aquariums, universities, research facilities and zoos throughout the world. Many entertainment parks are also regular users of FritzZyme®. To these professionals, having a reliable product to establish and maintain their systems is of vital importance. They rely on FritzZyme®.

  • What other products may be used with FritzZyme®?

    Chlorine must be removed before adding FritzZyme® (chlorine kills bacteria). FritzGuard® or Fritz Chlorine Remover may be used for this purpose. Fritz pH blocks for pH control, Fritz Super Salt for marine systems, Fritz Super Clarifier and Fritz Trace Elements may also be used without any adverse effect to the biofilter.

  • Why does it take so long for an aquarium to cycle without FritzZyme®?

    In comparison to other types of bacteria, nitrifying bacteria grow very slowly. Under optimal conditions, it takes fully 15 hours for a colony to double in size! By adding FritzZyme® nitrifying bacteria, you are adding bacteria to your system in amounts that would have taken weeks to naturally grow.

  • What about sludge removers?

    Sludge removers are not necessary in new systems because there is no organic material for them to break down. However, in established systems, they are beneficial; they will break down the organic material trapped in the biofilter. This trapped material cuts down the flow of oxygen-rich water to the nitrifying bacteria “the real workhorses of the aquarium.” Fritz offers sludge remover, FritzZyme® 360, a freshwater biological aquarium cleaner, for this purpose. Thus you can provide nitrifying bacteria and sludge removing bacteria as needed in your system.

  • What levels of ammonia and nitrite should I see when using FritzZyme®?

    You will see the normal “new tank syndrome” time greatly reduced or completely eliminated. The ammonia and nitrite levels, if present, will be well below stress levels. Problem systems will recover in a matter of days without extensive water changes.

  • How does FritzZyme® work?

    FritzZyme® allows your tank to duplicate nature. FritzZyme® “seeds” the biological filter with sufficient numbers of beneficial nitrifying bacteria so it can begin to remove ammonia and nitrite. Because the time required for the bacteria to become established is drastically reduced, fish may be introduced much sooner. When adding more fish or other bio-load to an aquarium, the addition of FritzZyme® adds more bacteria to the biofilter, thus preparing it to be able to handle the increased ammonia production.

  • How often should I use FritzZyme®?

    After the initial dosage of FritzZyme® to seed the biofilter, additions are only needed if more animals are added to the system, the efficiency of the biofilter has been reduced by medications or the biofilter has been disturbed (e.g., changing the media of a canister filter).

  • What if my nitrites will not go down in my freshwater aquarium treated with FritzZyme®?

    In freshwater, we occasionally run across this situation, and the first thing we recommend is testing your alkalinity. In aquariums with an alkalinity below a 4.5 dKH (1.6 Meq/l), the bacteria that convert the nitrite to nitrate simply stop the conversion process. We have found that after raising alkalinity to a minimum of 4.5 dKH (1.6 Meq/l) but ideally 5.6 dKH (2.0 Meq/l), nitrite conversion proceeds rapidly. In very, very rare cases the nitrite portion of the cycle remains stalled. In that situation, check your phosphate levels. Nitrifying bacteria, like all living organisms, need trace amounts of phosphate to function. A fishless cycle using ammonium chloride and RO/DI water may have 0.00ppm phosphates and will not complete the cycle. Even a trace amount of phosphate will allow the nitrifying bacteria to rapidly convert nitrite to nitrate. Fish food is a source of phosphate and Fritz pH Neutralizer contains phosphates. ⅛ to ¼ the standard dose would provide enough phosphate for nitrite conversion.

  • Will this product eliminate nitrates and phosphates in my aquarium?

    Not directly. However, they do consume organics that become nitrates in the aquarium, this slowing the accumulation of nitrates.

  • What happens if I overdose this product?

    Nothing negative. These bacteria are beneficial and naturally occurring and won’t harm anything and unless there was a truly massive overdose (20x or more) there will be no problems. The bacterial populations will only be as large as can be supported by the food source, so the worst that happens is they die back to levels that are sustainable.

  • Will FritzZyme® kill algae?

    Not directly. What the bacteria in FritzZyme® will do is compete with algae for the organic nutrients that act as a fertilizer for algae. Thus, over several months, you will see algae growth gradually recede and become less of a nuisance. However, if you have extreme algae growth in your aquarium when you start to use the FritzZyme® products, you will likely have to take other measures to reduce algae in the aquarium.

  • Does this product replace water changes?

    No. Over time, you will find that you can reduce water changes but this product is not intended to replace water changes. Your test kits (nitrate in particular) will indicate when you need water changes.

  • I added your product a couple of days ago, and I don’t see any difference! There’s still sludge everywhere in my aquarium!

    FritzZyme® introduces beneficial heterotrophic bacteria into your aquarium. When added to the aquarium, these bacteria are still in protective spore form. On entering the aquarium, they emerge from spore form but still need time to settle on a surface area and form colonies before getting to work. That’s why we recommend turning off UV sterilizers, etc. for 48 hours after adding. Even after forming colonies, it takes time for the bacteria to reduce the waste in the aquarium. Most users report improvement within two weeks and significant improvement over the course of a month.

  • Why must FritzZyme® 360/460 and MONSTER 360/460 be added to the aquarium on a regular basis? With FritzZyme® 7 & 9, I add it once and I’m done!

    This is a great question, and it is a little complex to answer because it varies from aquarium to aquarium. Each person’s aquarium will have slightly different chemical and biological composition and ecology. Some factors in play are: *Other bacteria species prey on the heterotrophs in FritzZyme® requiring the addition of more colonies over time. *As food levels (organics) are reduced by the bacteria in FritzZyme®, they die back somewhat. But the aquarist is constantly adding more nutrients to the aquarium in the form of food for fish. Adding more FritzZyme® keeps population levels relatively stable in the aquarium. *Power outages, medication usage and aquarium moves all impact bacterial populations. *Changes in the amount of livestock in the aquarium increase waste levels.

  • I received my product mail order and it was frozen! Is it still good?

    Yes, these heterotrophic bacteria form spores which can survive freezing. Let the product defrost gradually, shake well and use as directed.

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